منابع مشابه
Impaired collateral development in mature rats.
The effect of maturation on collateral development of resistance arteries was investigated. Three to four sequential mesenteric arteries were ligated to create collateral pathways in anesthetized young (approximately 200 g) and mature (approximately 600 g) rats. Blood flow was similarly elevated in collaterals of young and mature animals. In vivo inner arterial diameter was increased only withi...
متن کاملTemporal dependence of coronary collateral development.
OBJECTIVE Previous evidence suggests that episodes of myocardial ischemia of sufficient duration and intensity are required to produce coronary collateral development during repetitive coronary occlusion. This investigation tested the hypothesis that coronary collateral development is also temporal-dependent. METHODS Chronically instrumented dogs (n = 16) were subjected to brief (2 min) left ...
متن کاملRecent insights into human coronary collateral development.
Enhancement of coronary collateral function is an intriguing approach to the preservation of ischaemic myocardium. Coronary collateral development consists of collateral recruitment and collateral growth. Collateral growth encompasses proliferation of capillaries in the ischaemic area (angiogenesis) and maturation of pre-existing collateral vessels (arteriogenesis), with the latter being more r...
متن کاملThe human coronary collateral circulation: development and clinical importance.
Coronary collaterals are an alternative source of blood supply to myocardium jeopardized by ischaemia. In comparison with other species, the human coronary collateral circulation is very well developed. Among individuals without coronary artery disease (CAD), there are preformed collateral arteries preventing myocardial ischaemia during a brief vascular occlusion in 20-25%. Determinants of such...
متن کاملControlling collateral development: the difficult task of mimicking mother nature.
a , b c * Lino M. Gonçalves , Stephen E. Epstein , Jan J. Piek Department of Cardiology, Coimbra University Hospital, 3049 Coimbra Codex, Portugal Cardiovascular Research Institute of the MedStar Research Institute, Washington Hospital Center, 110 Irving Street, NW, Suite 4B1, Washington DC, USA Hartcatheterisatie B2-109, Academisch Medisch Centrum, Meibergdreef 9, 1105 AZ Amsterdam, The Nether...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 2014
ISSN: 0009-7330,1524-4571
DOI: 10.1161/circresaha.114.303402